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Fioricet is a combination medication which consists of butalbital, acetaminophen, caffeine and it is used to treat tension headaches. Acetaminophen helps to decrease the pain from the headache. Caffeine helps increase the effects of acetaminophen. Butalbital is a sedative that helps to decrease anxiety and cause sleepiness and relaxation.

Fioricet Oral Side Effects

Nausea, vomiting, abdominal pain, shaking (tremor), shortness of breath, lightheadedness, dizziness, or drowsiness may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. To lower your risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes, fainting, seizure, fast/irregular heartbeat, increased thirst/urination. Tell your doctor immediately if any of these rare but very serious side effects occur: signs of infection (e.g., fever, persistent sore throat), easy bruising/bleeding, change in the amount of urine. If you do not have liver problems, the adult maximum dose of acetaminophen is 4 grams per day (4000 milligrams). If you take more than the maximum daily amount, it may cause serious (possibly fatal) liver disease. Seek immediate medical attention if you have any of the following symptoms of liver damage: persistent nausea/vomiting, yellowing eyes/skin, dark urine, severe stomach/abdominal pain, extreme tiredness. If you have liver problems, consult your doctor or pharmacist for a safe dosage of this medication. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

The following side effects are associated with Fioricet Oral: Common side effects of Fioricet Oral:

Irritation of the Stomach or Intestines Less Severe
Drowsiness Less Severe
Dizzy Less Severe

Infrequent side effects of Fioricet Oral:

Depression Severe
Sluggishness Severe
Confused Severe
Over Excitement Severe
Nightmares Less Severe
Incomplete or Infrequent Bowel Movements Less Severe
Feeling Faint Less Severe
Sensation of Spinning or Whirling Less Severe
Chronic Trouble Sleeping Less Severe
Involuntary Quivering Less Severe
Head Pain Less Severe
Fast Heartbeat Less Severe
Feel Like Throwing Up Less Severe
Throwing Up Less Severe
Nervous Less Severe
Easily Angered or Annoyed Less Severe
Anxious Less Severe

Rare side effects of Fioricet Oral:

Feeling of Throat Tightness Severe
Hepatitis Severe
Hepatitis caused by Drugs Severe
Inflammation of Skin caused by an Allergy Severe
Stevens-Johnson Syndrome Severe
Skin Rash with Sloughing Severe
Decreased Calcification or Density of Bone Severe
Loss of Memory Severe
Hallucination Severe
Rash Severe
Wheezing Severe
Trouble Breathing Severe
Life Threatening Allergic Reaction Severe
Giant Hives Severe
Reaction due to an Allergy Severe
Rickets Severe
Megaloblastic Anemia Severe
Decreased Blood Platelets Severe
Deficiency of Granulocytes a Type of White Blood Cell Severe
Decreased White Blood Cells Severe
Decreased Neutrophils a Type of White Blood Cell Severe
Taking Habit Forming Drugs Less Severe
Discolored Spots and Small Elevations of the Skin Less Severe
Perform Complex Natural behaviors while Asleep Less Severe
Hives Less Severe
Uncoordinated Less Severe
Diarrhea

Less Severe

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medication because very serious interactions may occur: sodium oxybate.   If you are currently using the medication listed above, tell your doctor or pharmacist before starting this medication.   Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: adenosine, anti-seizure drugs (e.g., carbamazepine, phenytoin), beta agonists (e.g., albuterol), drugs affecting liver enzymes that remove this medication from your body (such as macrolide antibiotics including erythromycin, cimetidine, disulfiram, valproic acid, fluvoxamine, MAO inhibitors including furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine), isoniazid, lithium, methoxyflurane, phenothiazines (e.g., chlorpromazine).   This drug can speed up the removal of other drugs from your body by affecting certain liver enzymes. These affected drugs include “blood thinners” (e.g., warfarin), cyclosporine, corticosteroids such as prednisone, estrogen, felodipine, metronidazole, quinidine, certain beta blockers such as metoprolol, theophylline, doxycycline.   Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as certain antihistamines (e.g., diphenhydramine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., risperidone, amitriptyline, trazodone).   Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain caffeine or drowsiness-causing ingredients. Also keep in mind that certain beverages (e.g., coffee, colas, tea) contain caffeine. Ask your pharmacist about using those products safely.   Acetaminophen is an ingredient in many nonprescription products and in some combination prescription medications. Read the labels carefully before taking other pain relievers, fever reducers, or cold products to see if they also contain acetaminophen. Consult your pharmacist if you are uncertain whether your other prescription or nonprescription products contain acetaminophen. (See also adult maximum daily dose information in Side Effects section.)   This medication may decrease the effectiveness of combination-type birth control pills. This can result in pregnancy. Ask your doctor or pharmacist for details, and discuss whether you should use additional reliable birth control methods while taking any of these drugs.   This medication may interfere with certain medical/laboratory tests (including urine 5-HIAA levels, urine VMA levels, urine catecholamine levels, dipyridamole-thallium imaging tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.   This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Patient Reviews:

1. Reviewer: missyvette1, 45-54 Female on Treatment for 5 to less than 10 years (Patient) Thhis works 90 per cent of the time, as long as you take it as soon as you feel the headache coming. Only thing, you will test for abnormal liver enzymes, I tested for years and no one ever said that the meds were doing it. The retested over and over and ran different blood work, the last thing they wanted to do was a liver biopsy!! Now, I am trying to, after ten years, to try something different! Magnesium, B-12 and COQenzyme is supposed to prevent migraines. Hope it will work! 2.Reviewer: Beacbum83@aol.com, 25-34 Female. I have suffered with migraines since i was 9.Throughtout my life i have tried a mass variety of different over the counter drugs,they did absolutely nothing. A few weeks ago i went to the dr. and had myself looked at, was unable to stand the pain any longer, it was interfering with my life. I was prescribed fioricet, tried to have an open mind maybe this medication would actually help me, it did. The first time i took it, it made me feel a little funny but pretty soon i was sleeping and out of pain and that for me is absoulety amazing. I would however like to find the cause for my headaches, but in the mean time i think this drug will help me be me again.   3.Reviewer: 55-64 Female on Treatment for 5 to less than 10 years (Patient):I have had migraines since my teens. Six years ago I had, what I thought was a migraine, go extremely bad and had two brain bleeds/stroke. Please don’t ignore a sudden worse than migraine headache! Fioricet was prescribed for the daily headaches afterwards and has saved my daily existence. I now take them only as needed but am not addicted as some say. I agree that some drs want to not prescribed them lately and give you xanax instead which is addictive. I’ll take fioricet.